This conference will cover the fundamentals, recent advances and emerging issues related to mechanobiology. It will provide a unique opportunity to advance knowledge and understanding in the area of force-sensing in biology. This field intrinsically implies interdisciplinary approaches combining biology with physics, optics and computer modeling. Moreover, mechanobiology is being increasingly appreciated as being of primary importance in a plethora of biological processes, including development and cancer.

How living cells are able to sense their environment and adequately respond in terms of shape, migration, proliferation, differentiation, and survival remains one of the most fascinating issues in cell biology. This is particularly obvious in the context of embryonic development, where the complex architectural multi-scale organization of tissues is elaborated. Conversely, tumor evolution and metastasis is associated to dysfunctions of cell adhesion that frequently lead to the loss of tissue homeostasis. Thus, numerous and various biological processes (e.g. morphogenesis, tissue repair, and cancer invasion) are governed by the response of mechanical signals and their conversion into biochemical ones. Several general features emerge from these descriptions that seem to be of a very universal nature. During this conference, we propose to cover a large spectrum of these aspects. In particular, the conference will provide an overview of the mechanosensitive signaling pathways at the level of single cell and tissues, with a detailed description of the original experimental methods commonly used in this field, as well as including presentation of the necessary theoretical approaches in order to understand and model force generation and propagation in active biological matter.


Scientific Organizing Committee

Ada Cavalcanti
University of Heidelberg
Max Planck Institute
for Intelligent Systems

Benoit Ladoux
University Paris Diderot, CNRS, France
Mechanobiology Institute, Singapore
René-Marc Mège
University Paris Diderot & CNRS
Pierre Nassoy
Bordeaux University & CNRS
GV. Shivashankar
Mechanobiology Institute, Singapore
IFOM, Italy
Yusuke Toyama
Mechanobiology Institute
Jie Yan
Mechanobiology Institute

Invited speakers

MaximeDahan DennisEDischer

Maxime Dahan
Physico-Chimie Curie, Institut Curie
Paris, France

Dennis E. Discher
School of Medicine
University of Pennsylvania


SuzanneEaton TaekjipHa

Suzanne Eaton
The Max Planck Institute of
Molecular Cell Biology and Genetics

Dresden, Germany

Taekjip Ha
Johns Hopkins University
Baltimore, USA

SallyHorneBadovinac Michael Kozlov

Sally Horne-Badovinac
University of Chicago
Chicago, USA

Mickael Kozlov
Telaviv University

Mian Long RobertoMayor

Mian Long
Institute of Mechanics
Chinese Academy of Sciences
Beijing, China

Roberto Mayor
Research Department of Cell and
Developmental Biology
University College London, U


Prof. Michael Sheetz, Lasker Prize awardee in his lab at Columbia

Maithreyi Narasimha
Department of Biological Sciences
Tata Institute of Fundamental Research
Mumbai, India

Michael P. Sheetz
Mechanobiology Intitute, NUS Singapore

AnaSuncanaSmith Takeichi

Ana Suncana-Smith
Institut für Theoretische Physik
Universität Nürnberg-Erlangen, Germany

Masatochi Takeichi
Riken Center for Developmental Biology
Kobe, Japan

Conference venue

The conference will be organized at the International Center for Interdisciplinary Science and Education in Vietnam (ICISE) by Rencontres du Vietnam, a scientific non-profit organization. The venue is located at a beautiful beach in Vietnam, thus allowing participants also to enjoy the nature, culture while having rich scientific discussion. Information can be found here: http://rencontresduvietnam.org/introduction/.

Supporting Institutions

Institut Jacques Monod, Paris Max Planck Institute
Mechanobiology Institute, Singapore CoB_logo Fluigent
Alvéole LogoWhoamI_ VERT-01 L'Oréal Research & Innovation
JCBorangeletter_whitebkgd CNRS jpk-logo


For questions regarding the scientific program, please contact:

Benoît Ladoux (benoit.ladoux@univ-paris-diderot.fr)

René-Marc Mège (Rene-Marc.Mege@ijm.fr)

Ada Cavalcanti (ada.cavalcanti-adam@urz.uni-heidelberg.de)

Yusuke Toyama (dbsty@nus.edu.sg)

For administrative information, please contact:

Aimie Fong (rencontres.vietnam@gmail.com)
Secretary of the Rencontres du Vietnam

BP 33, F-91192, Gif sur Yvette, France
Tel: 33 (0)1 69 28 51 35 / 33(0)7 81 29 44 15